Moxonidine improves cardiac structure and performance in SHR through inhibition of cytokines, p38 MAPK and Akt
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چکیده
منابع مشابه
p38 MAPK and PI3K/AKT signalling cascades in Parkinson’s disease
Parkinson's disease (PD) is a chronic neurodegenerative condition which has the second largest incidence rate among all other neurodegenerative disorders barring Alzheimer's disease (AD). Currently there is no cure and researchers continue to probe the therapeutic prospect in cell cultures and animal models of PD. Out of several factors contributing to PD prognosis, the role of p38 MAPKs (mitog...
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parkinson's disease (pd) is a chronic neurodegenerative condition which has the second largest incidence rate among all other neurodegenerative disorders barring alzheimer's disease (ad). currently there is no cure and researchers continue to probe the therapeutic prospect in cell cultures and animal models of pd. out of several factors contributing to pd prognosis, the role of p38 mapks (mitog...
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15 صفحه اولMycophenolic acid inhibits mesangial cell activation through p38 MAPK inhibition.
Mesangial cell (MC) proliferation and extracellular matrix (ECM) accumulation are major pathologic features of chronic renal disease including chronic allograft nephropathy (CAN). Mycophenolic acid (MPA), a potent immunosuppressant, has emerged as a treatment to prevent CAN because it inhibits MC proliferation and ECM synthesis, but the mechanism involved has not been clarified. The present stu...
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ژورنال
عنوان ژورنال: British Journal of Pharmacology
سال: 2011
ISSN: 0007-1188
DOI: 10.1111/j.1476-5381.2011.01355.x